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Benefits of Alkaline, Ionized Water
By Dr. Hidemitsu Hayashi, M.D.
Director, Water Institute of Japan
Director, Water Institute of Japan
Nisshin Building, 2-5-10 Shinjiku,
Shinjiku-ku, Tokyo, Japan 160  

Why Drink Alkaline Ionized Water?
The Basics
Water, The chemistry of life.  
Whenever we attempt to determine whether there is life as we know it on Mars or
other planets, scientists first seek to establish whether or not water is present.
Why? Because life on earth totally depends on water.
A High percentage of living things, both plant and animal are found in water. All
life on earth is thought to have arisen from water. The bodies of all living
organisms are composed largely of water. About 70 to 90 percent of all organic
matter is water.
The chemical reactions in all plants and animals that support life take place in a
water medium. Water not only provides the medium to make
these life sustaining reactions possible, but water itself is often
an important reactant or product of these reactions. In short,
the chemistry of life is water chemistry.
Water, the universal solvent
Water is a universal, superb solvent due to the marked polarity of the water
molecule and its tendency to form hydrogen bonds with other molecules. One
water molecule, expressed with the chemical symbol H2O, consists of 2 hydrogen
atoms and 1 oxygen atom.
Standing alone, the hydrogen atom contains one positive
proton at its core with one negative electron revolving
around it in a three-dimensional shell. Oxygen, on the other
hand, contains 8 protons in its nucleus with 8 electrons
revolving around it. This is often shown in chemical
notation as the letter O surrounded by eight dots
representing 4 sets of paired electrons.
The single hydrogen electron and the 8 electrons of
oxygen are the key to the chemistry of life because this is where hydrogen and
oxygen atoms combine to form a water molecule, or split to form ions.
Hydrogen tends to ionize by losing its single electron and form single H+ ions,
which are simply isolated protons since the hydrogen atom contains no neutrons.
A hydrogen bond occurs when the electron of a single hydrogen atom is shared
with another electronegative atom such as oxygen that lacks an electron.
Polarity of water molecules
In a water molecule, two hydrogen atoms are covalently bonded to the oxygen
atom. But because the oxygen atom is larger than the hydrogen's, its attraction
for the hydrogen's electrons is correspondingly greater so the electrons are
drawn closer into the shell of the larger oxygen atom and away from the
hydrogen shells. This means that although the water molecule as a whole is
stable, the greater mass of the oxygen nucleus tends to draw in all the electrons
in the molecule including the shared hydrogen electrons giving the oxygen
portion of the molecule a slight electronegative charge.
The shells of the hydrogen atoms, because their electrons are closer to the
oxygen, take on a small electropositive charge. This means water molecules
have a tendency to form weak bonds with water molecules because the oxygen
end of the molecule is negative and the hydrogen ends are positive.
A hydrogen atom, while remaining covalently bonded to the oxygen of its own
molecule, can form a weak bond with the oxygen of another molecule. Similarly,
the oxygen end of a molecule can form a weak attachment with the hydrogen
ends of other molecules. Because water molecules have this polarity, water is a
continuous chemical entity.
These weak bonds play a crucial role in stabilizing the shape of many of the large
molecules found in living matter. Because these bonds are weak, they are readily
broken and re-formed during normal physiological reactions. The disassembly
and re-arrangement of such weak bonds is in essence the chemistry of life.
To illustrate water's ability to break down other substances,
consider the simple example of putting a small amount of
table salt in a glass of tap water. With dry salt (NaCl) the
attraction between the electropositive sodium (Na+) and
electronegative chlorine (Cl-) atoms of salt is very strong
until it is placed in water. After salt is placed in water, the
attraction of the electronegative oxygen of the water
molecule for the positively charged sodium ions, and the
similar attraction of the electropositive hydrogen ends of the
water molecule for the negatively charged chloride ions, are
greater than the mutual attraction between the outnumbered Na+ and Cl- ions. In
water the ionic bonds of the sodium chloride molecule are broken easily because
of the competitive action of the numerous water molecules.

As we can see from this simple example, even the delicate configuration of
individual water molecules enables them to break relatively stronger bonds by
converging on them. This is why we call water the universal solvent. It is a
natural solution that breaks the bonds of larger, more complex molecules. This is
the chemistry of life on earth, in water and on land.
Oxidation-reduction reactions
Basically, reduction means the addition of an electron (e-), and its converse,
oxidation means the removal of an electron. The addition of an electron,
reduction, stores energy in the reduced compound. The removal of an electron,
oxidation, liberates energy from the oxidized compound. Whenever one
substance is reduced, another is oxidized.

To clarify these terms, consider any two molecules, A and B, for example.  
When molecules A and B come into contact, here is what happens:
B grabs an electron from molecule A.  
Molecule A has been oxidized because it has lost an electron.
The net charge of B has been reduced because it has gained a negative electron
In biological systems, removal or addition of an electron constitutes the most
frequent mechanism of oxidation-reduction reactions. These oxidation-reduction
reactions are frequently called redox reactions.  
Acids and Bases
An acid is a substance that increases the concentration of hydrogen ions (H+) in
water. A base is a substance that decreases the concentration of hydrogen ions,
in other words, increasing the concentration of hydroxide ions OH-.
The degree of acidity or alkalinity of a solution is measured in terms of a value
known as pH, which is the negative logarithm of the concentration of hydrogen
pH = 1/log[H+] = -log[H+]  
What is pH?
On the pH scale, which ranges from 0 on the acidic end to 14 on the alkaline end,
a solution is neutral if its pH is 7. At pH 7, water contains equal concentrations of
H+ and OH- ions. Substances with a pH less than 7 are acidic because they
contain a higher concentration of H+ ions. Substances with a pH higher than 7
are alkaline because they contain a higher concentration of OH- than H+. The pH
scale is a log scale so a change of one pH unit means a tenfold change in the
concentration of hydrogen ions.
Importance of balancing pH
Living things are extremely sensitive to pH and function best (with certain
exceptions, such as certain portions of the digestive tract) when solutions are
nearly neutral. Most interior living matter (excluding the cell nucleus) has a pH of
about 6.8.

Blood plasma and other fluids that surround the cells in the body have a pH of
7.2 to 7.3. Numerous special mechanisms aid in stabilizing these fluids so that
cells will not be subject to appreciable fluctuations in pH. Substances which
serve as mechanisms to stabilize pH are called buffers. Buffers have the capacity
to bond ions and remove them from solution whenever their concentration begins
to rise. Conversely, buffers can release ions whenever their concentration begins
to fall. Buffers thus help to minimize the fluctuations in pH. This is an important
function because many biochemical reactions normally occurring in living
organisms either release or use up ions.  
NOTE: Dr. Hayashi is a Heart Specialist and Director of the Water Institute of
Oxygen: Too much of a good thing?
Oxygen is essential to survival. It is relatively stable in the air, but when too much
is absorbed into the body it can become active and unstable and has a tendency
to attach itself to any biological molecule, including molecules of healthy cells.
The chemical activity of these free radicals is due to one or more pairs of
unpaired electrons.
About 2% of the oxygen we normally breathe becomes active oxygen, and this
amount increases to approximately 20% with aerobic exercise.
Such free radicals with unpaired electrons are unstable
and have a high oxidation potential, which means they
are capable of stealing electrons from other cells. This
chemical mechanism is very useful in disinfectants such
as hydrogen peroxide and ozone which can be used to
sterilize wounds or medical instruments. Inside the body
these free radicals are of great benefit due to their ability
to attack and eliminate bacteria, viruses and other waste products.
Active Oxygen in the body
Problems arise, however, when too many of these free radicals are turned loose
in the body where they can also damage normal tissue.
Putrefaction sets in when microbes in the air invade the proteins, peptides, and
amino acids of eggs, fish and meat. The result is an array of unpleasant
substances such as:
Hydrogen sulfide  
These substances are also produced naturally in the digestive tract when we
digest food, resulting in the unpleasant odor evidenced in feces. Putrefaction of
spoiled food is caused by microbes in the air; this natural process is duplicated in
the digestive tract by intestinal microbes. All these waste products of digestion
are pathogenic, that is, they can cause disease in the body.
Hydrogen sulfide and ammonia are tissue toxins that can damage the liver.
Histamines contribute to allergic disorders such as atopic dermatitis, urticaria
(hives) and asthma. Indoles and phenols are considered carcinogenic. Because
waste products such as hydrogen sulfide, ammonia, histamines, phenols and
indoles are toxic, the body's defense mechanisms try to eliminate them by
releasing neutrophils (a type of leukocyte, or white corpuscle). These neutrophils
produce active oxygen, oddball oxygen molecules that are capable of scavenging
disintegrating tissues by gathering electrons from the molecules of toxic cells.
Problems arise, however, when too many of these active oxygen molecules, or
free radicals, are produced in the body. They are extremely reactive and can also
attach themselves to normal, healthy cells and damage them genetically. These
active oxygen radicals steal electrons from normal, healthy biological molecules.
This electron theft by active oxygen oxidizes tissue and can cause disease.

Because active oxygen can damage normal tissue, it is essential to scavenge
this active oxygen from the body before it can cause disintegration of healthy
tissue. If we can find an effective method to block the oxidation of healthy tissue
by active oxygen, then we can attempt to prevent disease.

Antioxidants block dangerous oxidation
One way to protect healthy tissue from the ravages of oxidation caused by active
oxygen is to provide free electrons to active oxygen radicals, thus neutralizing
their high oxidation potential and preventing them from reacting with healthy
Research on the link between diet and cancer is far from complete, but some
evidence indicates that what we eat may affect our susceptibility to cancer. Some
foods seem to help defend against cancer, others appear to promote it.
Much of the damage caused by carcinogenic substances in food may come
about because of an oxidation reaction in the cell. In this process, an oddball
oxygen molecule may damage the genetic code of the cell. Some researchers
believe that substances that prevent oxidation -- called ANTIOXIDANTS -- can
block the damage. This leads naturally to the theory that the intake of natural
antioxidants could be an important aspect of the body's defense against cancer.
Substances that some believe inhibit cancer include vitamin C, vitamin E, beta-
carotene, selenium, and gluthione (an amino acid). These substances are
reducing agents. They supply electrons to free radicals and block the interaction
of the free radical with normal tissue.
How we can avoid illness
As we mentioned earlier, the presence of toxic waste products such as hydrogen
sulfide, ammonia, histamines, indoles, phenols and scatoles impart an offensive
odor to human feces. In the medical profession, it is well known that patients
suffering from hepatitis and cirrhosis pass particularly odoriferous stools.
Excessively offensive stools caused by the presence of toxins are indicators of
certain diseases, and the body responds to the presence of these toxins by
producing neutrophil leukocytes to release active oxygen in an attempt to
neutralize the damage to organs that can be caused by such waste products. But
when an excess amount of such active oxygen is produced, it can damage
healthy cells as well as neutralize toxins. This leads us to the conclusion that we
can minimize the harmful effect of these active oxygen radicals by reducing them
with an ample supply of electrons.
Water, the natural solution
There is no substitute for a healthy balanced diet, especially rich in antioxidant
materials such as vitamin C, vitamin E, beta-carotene, and other foods that are
good for us. However, these substances are not the best source of free electrons
that can block the oxidation of healthy tissue by active oxygen.
Water treated by electrolysis to increase its reduction potential is the best
solution to the problem of providing a safe source of free electrons to block the
oxidation of normal tissue by free oxygen radicals. We believe that reduced water,
water with an excess of free electrons to donate to active oxygen, is the best
solution because:
The reduction potential of water can be dramatically increased over other
antioxidants in food or vitamin supplements.  
The molecule weight of reduced water is low, making it fast acting and able to
reach all tissues of the body in a very short time.  
Ionized water is the product of mild electrolysis which takes place in the ionized
water unit. The production of ionized water, its properties, and how it works in the
human body are described in the next section. Ionized water is treated tap water
that has not only been filtered, but has also been reformed in that it provides
reduced water with a large mass of electrons that can be donated to active
oxygen in the body to block the oxidation of normal cells.
Tap water: What it is and isn't
Normal tap water, for example, with a pH of 7 is approximately neutral on the pH
scale of 0 to 14. When measured with an ORP (oxidation potential) meter its
redox potential is approximately +400 to +500 mV. Because it has a positive
redox potential, it is apt to acquire electrons and oxidize other molecules.
Reduced Ionized Water, on the other hand, has a negative redox potential of
approximately -250 to -350 mV. This means it has a large mass of electrons
ready to donate to electron-thieving active oxygen.
Before discussing the properties of Ionized Water further, let's take a look at what
happens inside an Ionized Water producing unit.
How an IONIZED WATER Unit works
The Ionized Water unit, slightly taller and thicker than a large dictionary on end,
is an electrical appliance connected to your kitchen water supply to perform
electrolysis on tap water before you drink it or use it in the kitchen for cooking or

A special attachment re-directs tap water out of the faucet through a plastic hose
into the Ionized Water unit. Inside the Ionized Water unit, the water is first filtered
through activated charcoal. Next, the filtered water passes into an electrolysis
chamber equipped with a platinum-coated titanium electrode where electrolysis
takes place.
Cations, positive ions, gather at the negative electrodes to create cathodic water
(reduced water). Anions, negatively charged ions, gather at the positive electrode
to make anodic water (oxidized water).

Through electrolysis, reduced water not only gains an excess amount of
electrons (e-), but the cluster of H 2O seem to be reduced in size from about
10 to 13 molecules per cluster to 5 to 6 molecules per cluster.
The reduced water comes out of the faucet, and the oxidized water comes out of
a separate hose leading into the sink. You can use the reduced water for drinking
or cooking. The oxidation potential of the oxidized water makes it a good
sterilizing agent, ideal for washing hands, cleaning food or kitchen utensils, and
treating minor wounds.
What the IONIZED WATER Unit Produces  
Redox potential comparison
After electrolysis of the water inside the Ionized Water unit, reduced water comes
out of the cathodic side and oxidized water comes out of the anodic side.
Compare these measurements of these three types of water: tap water before
electrolysis, the reduced water, and the oxidized water.

Redox potential, not pH, is the crucial factor
Traditionally we have judged the properties of water from the standpoint of pH, in
other words whether water is acidic or alkaline. According to Dr. Yoshiaki Matsuo
PhD., the inventor of the Ionized Water unit, "In my opinion, redox potential is
more important than pH. The importance of pH is over emphasized. For example,
the average pH of blood is 7.4 and acidosis or alkalosis are defined according to
deviation within the range of 7.4 +- 0.005. But nothing has been discussed about
ORP, or oxidation-reduction potential."
The pH of tap water is about pH 7, or neutral. When tap water is electrolyzed into
Ionized Water, its reduced water has a pH of about 9 and the oxidized water a
pH of about 4. Even if you make alkaline water of pH 9 by adding sodium
hydroxide or make acidic water of pH 3 by adding hydrogen chloride, you will find
very little change in the ORP values of the two waters. On the other hand, when
you divide tap water with electrolysis you can see the ORP fluctuate by as much
as +- 1,000 mV. By electrolysis we can obtain reduced water with negative
potential that is good for the body.

The Ionized Water unit produces two kinds of water with different redox
potentials, one with a high reduction potential and the other with a high oxidation
Reduced Water
When taken internally, the reduced Ionized Water with its redox potential of -250
to -350 mV readily donates its electrons to oddball oxygen radicals and blocks
the interaction of the active oxygen with normal molecules.

A biological molecule (BM) remains intact and undamaged.  
Undamaged biological molecules are less susceptible to infection and disease.
Ionized Water gives up an extra electron and reduces the active oxygen (AO),
thus rendering it harmless. The AO is reduced without damaging surrounding
biological molecules. Substances which have the ability to counteract active
oxygen by supplying electrons are called scavengers. Reduced water, therefore,
can be called scavenging water.
When taken internally, the effects of reduced water are immediate. Ionized Water
inhibits excessive fermentation in the digestive tract by reducing indirectly
metabolites such as hydrogen sulfide, ammonia, histamines, indoles, phenols
and scatoles, resulting in a cleaner stool within days after reduced water is taken
on a regular basis. In 1965, the Ministry of Welfare of Japan announced that
reduced water obtained from electrolysis can prevent abnormal
fermentation of intestinal microbes.
Oxidized Water
Oxidized water with its redox potential of +700 to +800 mV is an oxidizing agent
that can withdraw electrons from bacteria and kill them. The oxidized water from
the Ionized Water unit can be used to clean hands, kitchen utensils, fresh
vegetables and fruits, and to sterilize cutting boards and minor wounds. Tests
have shown that oxidized water can be used effectively to treat athlete's foot,
minor burns, insect bites, scratches, and so on.
Dr. Yoshiaki Matsuo, Vice Director of the Water Institute of Japan, has developed
another apparatus capable of producing hyperoxidized water with a redox
potential of +1,050 mV or more, and a pH lower than 2.7. Tests have shown that
this hyper oxidized water can quickly destroy MRSA (Methecillin Resistant
Staphylococcus Aureus).
Although hyperoxidized water is a powerful sterilizing agent, it won't harm the
skin. In fact, it can be used to heal. Hyperoxidized water has proven effective in
Japanese hospitals in the treatment of bedsores and operative wounds with
complicated infections.
But perhaps the most exciting future application of hyperoxidized water is in the
field of agriculture where it has been used effectively on plants to kill fungi and
other plant diseases. Hyperoxidized water is non-toxic, so agricultural workers
can apply it without wearing special protective equipment because there is no
danger of skin or respiratory damage. An added benefit of using hyperoxidized
water to spray plants is that there is no danger to the
environment caused by the accumulation of toxic
chemicals in the ground.
Ionized Water superior to antioxidant diet
Today we read much about correct dieting principles and
paying attention to what we eat in order to stay healthy. This is a sensible
practice, but it is surprising that many of us don't realize that the bulk of what eat
is composed of water. Vegetables and fruits are 90% water; fish and meat are
about 70% water as well.
Even advocates of the importance of vitamin C in diet staples have to admit that
its potency, namely, the redox potential of this important vitamin, rapidly
diminishes with age and preparation for the dining table. Carbohydrates, the
main consistent of vegetables and fruit, has a molecular weight of 180 whereas
water has a much lower molecular weight of 18.

Ionized Water, with its low molecular weight and high reduction potential, makes
it a superior scavenging agent of active oxygen. But electrolysis inside the
Ionized Water unit not only charges the reduced water with electrons, it also
reduces the size of reduced water molecule clusters.
NMR (Nuclear Magnetic Resonance) analysis reveals that tap water and well
water consists of clusters of 10 to 13 H2 0 molecules. Electrolysis of water in the
Ionized Water unit reduces these clusters to about half their normal size -- 5 to 6
water molecules per cluster.
As the graph shows, the NMR signal that measures cluster size by line width at
half-amplitude shows 65 Hz for reduced water and 133 Hz for tap water,
revealing that the reduced water clusters are approximately half the size of tap
water clusters.

This is why Ionized Water is more readily absorbed by the body than untreated
tap water. Ionized Water quickly permeates the body and blocks the oxidation of
biological molecules by donating its abundant electrons to active oxygen,
enabling biological molecules to replace themselves naturally without damage
caused by oxidation that can cause diseases.
Upstream and downstream theory
Prevent disease at the source
According to Dr. Hidemitsu Hayashi, Director of the Water Institute of Japan, "To
eliminate the pollutants in a large stream that is contaminated at its source, we
must work on the problems upstream at the headwaters -- the source of the
pollution -- not downstream where we can only try to treat the evidence of
damage caused by the pollution. Ionized Water's contribution to preventive
medicine is essentially upstream treatment."

According to our model, we consider the digestive tract upstream where we
intake water and food. Although many people today in developed countries are
growing more skeptical about what they eat, they tend to concentrate more on
what the food contains rather than the metabolized products of foods in the
digestive tract.

For example, consider the typical balanced diet of meat and
vegetables. Meat protein is metabolized into amines while
nitrates from fertilizers used to grow vegetables metabolize
into nitrites in the digestive tract. These amines and nitrites
combine to form nitrosamine, a recognized carcinogen.
We've already discussed that odoriferous feces are evidence
of excessive fermentation in the digestive tract, so reduced
water performs a very important function upstream in the
digestive tract by reducing this excessive fermentation as evidenced by cleaner
stools within days of starting a steady regimen of reduced water.

Downstream from the digestive tract, starting at the liver, reduced water quickly
enters the liver and other organs due to, first, its lower molecular weight, and,
secondly, the size of its clusters. At tissue sites throughout the body, reduced
water with its safe, yet potent reduction potential readily donates its passenger
electrons freely to active oxygen and neutralizes them so they cannot damage
the molecules of healthy cells. Normal cells are protected from the electron
thievery of active oxygen and allowed to grow, mature, function and regenerate
without interference from rogue, oddball oxygen radicals which tend to steal the
electrons from the molecules of normal, healthy biological molecules.
The water boom
We are now in the midst of a water boom. In Japan and other countries
consumers are buying various kinds of bottled and canned water even though
water is one of our most abundant vital resources. Research data reveals that
mineral waters have an ORP of +200 mV, slightly lower than the +400 mV
measured for ordinary tap water. We can say that at least mineral water is
marginally better than tap water from the viewpoint of ORP. Compared to any
processed water for sale, however, Ionized Water with its reduction potential of -
250 to -300 mV is beyond comparison due to its ability to scavenge active
oxygen radicals.